The Sackett Lab

BIOL8053: Special Topics – Microbial Genomics
Advances and decreasing costs of high-throughput DNA sequencing technologies have revolutionized the field of Biology. Not only do genomics analyses permit investigations into the metabolic potential, ecology, and evolutionary history; these techniques can be leveraged in microbiology to identify essential genes, to identify genes involved in cryptic metabolic pathways, and to evaluate directed evolution studies, among many other applications. Because of the ease of access and speed at which we can analyze a microbial genome, this course will use microbial genome annotation and assembly to provide an in-depth study on the methods of genome reconstruction, sequence annotation and analysis, and comparative genomics